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Duloxetine

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Q: duloxetine?

A: Generic for Cymbalta used to treat depression

Q: Does Lamotrigine and Duloxetine helps to improve my mood and my dizzyness?
Does Lamotrigine and Duloxetine helps to improve my mood and my dizzyness?and is there any side effect should i take any other medicine instead of this?

A: i have no answers but it is a good question.
I just started taking this med. The dr started me on 1/2 pill every day for 2 weeks, then 1/2 pill 2X a day for 2 weeks, (then i think 1 pill per day).

Q: Does anybody know about the manufacturing problems are with Duloxetine?
I have looked on the net and rung a few pharmasists but haven’t been able to find any information on why nobody can get supplies or how long the problem is going to go on for! Please can somebody help?
This may jsut be a problem in the UK, or south east england!
I found out today that it’s actually a wholesaler problem, so if anybody can explain why, if the company has no problems, they can’t just order more!

A: I did a quick wikipedia search, and it sounds like when Duloxetine was put into circulation it had unexpected and severe side-effects on lots of people. Although it had been initially given the ‘green light’ for a number of conditions, it’s list of applicable diseases dwindled sharply soon after its release. Check it out – the following is a quote from the webiste listed below.

Duloxetine (brand names Cymbalta, Yentreve) is a serotonin-norepinephrine reuptake inhibitor (SNRI) used for major depressive disorder (MDD), generalized anxiety disorder (GAD), pain related to diabetic neuropathy and in some countries for stress urinary incontinence (SUI). It is manufactured and marketed by Eli Lilly. Large number of side effects occurring during duloxetine treatment and lack of clear advantage over existing medications prompted critical reviews concluding that duloxetine “should not be used” for stress urinary incontinence[1] and “currently has no place in the treatment of depression or diabetic neuropathy” as well.[2][3]

Q: Is anyone else trying to come of the anti-depressant Duloxetine (Cymblta) and having problems?
I am feeling very light headed and havind vivid and violent dreams

A: It is a highly dependent anti-depressant. Has your gp given you anything else to help you come off it? I would go back and tell him whats happen and if you could have something to help you come off it. What you have described is you going cold turkey and it isn’t nice thing to go through.

Q: does Lamotrigine and Duloxetine helps me to improve my mood and my depression?
Iam taking this medicines since long and iam feeling better but not completely but ok and i want to know anyother medicine can help me faster than this medicne and the side effect of this medicine,
Pls advice me for better

A: look into Wild Kratom or Salvia dela Luz very powerful herbs. a lot of people are reporting positive results. site with info below. good luck.

Q: Is it possible to have a fatal od from Duloxetine (Cymbalta)?
Or what about any of the SSRI’s such as Citalopram (Celexa)? I know the old Tricyclic anti-depressants such as Amitriptyline are fairly easy to kill yourself with, but it is my understanding that most of the new ones won’t kill you.

Is this correct?
Thanks

A: If you OD on anything you are at risk. Even Tylenol. I suggest you take the prescribed dose and just stick with it.

Q: Does Lamotrigine and Duloxetine HCl medicine can cure depression without any side effect and fast recovery?
Iam using this medicine and its working but i want to know any sideeffect and better medicine than that on instead, pls help me

A: All anti depressants cause side effects. your Pharmacist can advise you concerning side effects and will be happy to do so.

Q: What’s the problem with Cymbalta – Duloxetine manufacutring problems as is causing stock shortage in chemists?
Does anyone know why there seems to be such a problem with pharmacies getting hold of this drug? as I have had to search round the country several times this year already…

A: Large number of side effects occurring during duloxetine treatment and lack of clear advantage over existing medications prompted critical reviews concluding that duloxetine “should not be used” for stress urinary incontinence and “currently has no place in the treatment of depression or diabetic neuropathy” as well.
Eli Lilly has withdrawn its supplemental New Drug Application (sNDA) from the U.S. Food and Drug Administration (FDA) for duloxetine (Cymbaltaâ„¢)

Q: What are all the side-effects of Cymbalta (Duloxetine HCI)?

A: Here are the results from the clinical trials:

http://www.rxlist.com/cymbalta-drug.htm

Try not to get too freaked out reading it, though. In clinical trials, *every* effect reported needs to be treated as a potential side effect, so it can sometimes make for rather alarming reading.

If you’re more interested in anecdotal accounts, askapatient is always a good place to look:

http://www.askapatient.com/viewrating.asp?drug=21427

(Do bear in mind, though, that people are far more likely to take the time to post on askapatient when they’ve had bad experiences with a drug than when they’ve not had any problems with side effects. So don’t let it scare you too much: if you just went by askapatient, you’d be amazed that aspirin is legal to sell over the counter!)

Crazymeds is often a good place to go to find relatively balanced descriptions of anti-depressants and their side effects:

http://www.crazymeds.us/cymbalta.html

I hope that helped.

Q: I know a person who is taking Olanzapine and Duloxetine who now is very overweight and gets blurred vision….?
could alternatives be recommended and would it be difficult to change?

A: It really depends on the individual. All antipsychotics carry the unfortunate side effect of weight gain, though my personal opinion puts zyprexa (olanzapine) at the top. The blurred vision could be a sign of toxicity (I’ve experienced that before and it was the problem) so I highly recommend consulting with the prescribing psychiatrist. It might be worth a second opinion too. Unfortunately, some drugs are overdone in the name of silencing the patient.

Q: Cymbalta ( duloxetine hydrochloride ) did it help you?
I have just been perscribed cymbalta and curious if it has actually helped because i hear alot of the time not to take anti-depressents that it makes matters worse.

A: My sister, uncle, and I all love it.It made my depression go completely away, and hindered the OCD for a while too, which was a bonus. My sister has tried dozens of meds, and she says the one which helped her the most was Cymbalta. We’re both on a high dose (120mg), but it’s worked miracles for us. I don’t know much about my uncle’s situation, except that he takes it and likes it.
I should add that all three of us are on multiple psychiatric meds
Mine: Seroquel 650mg, Cymbalta 120mg, Klonopin .5mg, Anafranil 100mg
Sister’s: Seroquel 200mg, Cymbalta 120mg, Adderall ?mg, Lithium ?mg
Uncle: Clozaril ?mg, Abilify ?mg, Cymbalta ?mg
So yeah, my uncle and I have schizophrenia, and my sister has extremely severe depression.
But the bottom line is that Cymbalta is awesome (None of us has had any side effects), and you won’t see that unless you try it.
And even if it’s not the one for you, there are plenty of other ones. I went through 5 or 6 antidepressants before finding the one that worked for me, so don’t give up trying meds until you’ve went through a few.
Good luck :)

Q: i am on duloxetine and tryptophan question about tiredness and halving tryptophan dose?
in the past couple of weeks i have noticed at about two o clock i am literally falling asleep at my desk i have to take a break in the loo

so instead of the full tryptophan dose 1500 morning and 1500 night i thought i would just take them at night three days ago

now i feel the panic attacks again

what would you reccomend

xxx vici

i have been on them about 18 months all tgether and i am 32 years old

ptsd ocd chronoic depression and panic attacks

A: Try to do these nature cure sincerely, you will be cured :

Depression, Tension & Increase of will-power.

Increasing the will-power : Our mind has a great effect on these glands. For example, continuous fear damages the Pituitary gland and makes one timid. Similarly,tension and worry disturb the Pineal gland and so leads to high B.P. and as Pineal gland controls other glands it also disturbs other glands and digestive system. In modern times, strees-tension or worry-fear have increased and they often disturb these endocrine glands. If these endocrine glands are not treated immediately, it might lead to malfunctioning of other glands of the body. As these glands are interrelated, whenever one gland is disturbed, the other glands also get disturbed. So, when you press on the points of these endocrine glands you will feel pain on points of more than one gland especially in case of chronic diseases. Therefore, it is very improtant to give Acupressure treatment on all the endocrine glands and keep them under proper control.

These glands also control the mind (the will-power). So in order to get rid of bad habits like smoking, drinking, drug addiction or even overeating, it is extremely necessary to give treatment on all endocrine glands for at least, fifteen days. Because, these people lack the necessary will-power to give up bad habits, they often break their vows to stop such bad habits and so they are considered unreliable. However, a treatment of fifteen days will give them necessary will-power to stop these bad habits after that. And they will be free from the withdrawal symptoms of stopping these bad habits.

Nervous tension : In the modern days because of fast life and loss of contentment,nervous tension keeps on building up increasingly, tending to damage our mind and health.

How to find out : Ask the patient to lie down on the back and ask some one to press on the base of the middle toe in both the legs. If there is a hurting sensation,it means nervous tension. If the hurting is unbearable, it means that the person is on the verge of collapse and needs immediate attention.

C U R E : (1) While the patient is lying on the back, bend all the toes of both legs, backward. It may hurt but give little more pressure and bend them as much as possible. Repeat this three times a day till the tension is removed.

(2) Clasp your hands tightly interlocking the fingers. Then with left hand fingers press on the back of the right hand and then with right hand fingers, press on the back of the left hand. repeat for about 1 to 2 minutes, 3 to 4 times a day.

(3) Insomnia : The above mentioned treatment can be taken for 5 to 12 minutes at night in bed to ensure good sleep and cure insomnia.

(4) Take 2 glasess of gold/cilver/copper charged water reduced from 8 glasses of water daily.

(5) Kali Phos 1 m (a Biochemic medicine) : Take 8 pills in the eveining between 8 to 9 p.m. for 10 days, then once a week. After 10 days Kali Phos 12 x 4+4 pills every day. Complete course is of 45 days.

Q: Registration of Yentreve (duloxetine) medicine for urinary incontinence in Slovenia. Is it already approved?

A: it was under FDA consideration in 2005 for incontinence, Now it is being used for depression at least, review this article and talk to your local doctor or local health department, good luck

Q: what are the side effects of ‘DUZELA’ ? (duloxetine hydrochloride)?
does this drug have any negative effect on your blood profile? esp. lowering of platelet count? or for that matter on body muscles, and does it cause fatigue in the patient too?

A: these are the same thing. check the link.
Cymbalta side effects

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe to continue using Cymbalta.

Side effects may include:
Appetite changes, constipation, diarrhea, dizziness, dry mouth, fatigue, headache, insomnia, nausea, sexual difficulties, sleepiness, sweating, tremor, urinary difficulties, vomiting, weakness

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Why should Cymbalta not be prescribed?

You will not be able to use Cymbalta if it causes an allergic reaction. In addition, you should not take Cymbalta if you have uncontrolled narrow-angle glaucoma, a disease that causes increased pressure in the eyes.

Never combine Cymbalta with an MAO inhibitor such as Marplan, Nardil, or Parnate (see “Most important fact about Cymbalta”).

Do not take the drug thioridazine (Mellaril) with Cymbalta, as it could cause fatal heartbeat irregularities.

——————————————————————————–

Special warnings about Cymbalta

In clinical studies, antidepressants increased the risk of suicidal thinking and behavior in children and adolescents with depression and other psychiatric disorders. Anyone considering the use of Cymbalta or any other antidepressant in a child or adolescent must balance this risk with the clinical need. Cymbalta has not been studied in children or adolescents and is not approved for treating anyone less than 18 years old.

Additionally, the progression of major depression is associated with a worsening of symptoms and/or the emergence of suicidal thinking or behavior in both adults and children, whether or not they’re taking antidepressants. Individuals being treated with Cymbalta and their caregivers should watch for any change in symptoms or any new symptoms that appear suddenly–especially agitation, anxiety, hostility, panic, restlessness, extreme hyperactivity, and suicidal thinking or behavior–and report them to the doctor immediately. Be especially observant at the beginning of treatment or whenever there is a change in dose.

Some medical conditions require careful monitoring during treatment with Cymbalta. Be sure to tell the doctor if you have diabetes, glaucoma, high blood pressure, or a seizure disorder. Cymbalta can cause episodes of mania (abnormally high feelings of excitement and energy), so be sure the doctor is aware if you have this condition.

Using Cymbalta is not recommended if you have liver problems or severe kidney disease.

Like other antidepressants, Cymbalta can cause drowsiness and affect judgment or motor skills. Use caution when driving, operating dangerous machinery, or participating in hazardous activities until you know how the drug affects you.

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Possible food and drug interactions when taking Cymbalta

Never take Cymbalta with MAO inhibitors (see “Most important fact about Cymbalta”) or the drug thioridazine (Mellaril). Consult your doctor first before taking drugs that act on the central nervous system, such as antipsychotics, narcotic painkillers, sleep inducers, or tranquilizers.

Due to the possibility of liver damage, do not take Cymbalta if you use alcohol more than occasionally.

If Cymbalta is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Cymbalta with the following:

Antibiotics known as quinolones, such as Cipro, Floxin, and Trovan
Antidepressants known as tricyclics, including Elavil, Pamelor, and Tofranil
Antidepressants that raise serotonin levels, such as Effexor, Paxil, Prozac, and Zoloft
Antipsychotic medication known as phenothiazines, including Compazine, Prolixin, Serentil, Thorazine, and Trilafon
Flecainide (Tambocor)
Fluvoxamine
Propafenone (Rythmol)
Quinidine

Q: I know a person who is taking Olanzapine and Duloxetine (Cymbalta), are there alternatives please?…..?
Which won’t cause weight gain and blurred vision? and would it be easy to change the medication?
The blurred vision is there every day…..

A: Side effects normally lessen or go away.
Weight can be stabilized with diet and exercise.
Drink plenty of water.

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